In 1969, philosopher Marshall McLuhan argued that the interest in psychedelics at the time had to do with developing “empathy with the invading electronic environment.” Today’s “psychedelic renaissance” is led by experimentation in the therapeutic effects of mind-altering drugs. On February 22, 2021, film Faculty member, Patricia Pisters, explained during an online session of SPUI25 how this renaissance” also tells us something about a new understanding of our complex digital living environment that is increasingly permeated by artificial intelligence and media machinations.